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Overall Evidence for the Use of B12 for Painful Entrapment Neuropathies Taking into account the above evidence, there is level III evidence overall to support the use of B12 as part of a combination vitamin regime for treating neuropathic pain caused by entrapment neuropathies

Neuroprotective Properties Under Investigation The Zagreb groups 2016 review in Current Neuropharmacology described peripheral BPC-157 administration altering serotonin synthesis rates in specific brain regions, particularly nigrostriatal and other dopaminergic pathways (Tohyama, Sikiric, Diksic, 2004, Life Sciences )

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